Chelist HOME
Search all list by Chemical ID
Search all list by Chemical Structure
Find the overlap between selected chemical list
Combine chemical list into a custom list
Click on cas number to get more details
ECVAMes_Positives List: ECVAM Ames Positives List: EURL ECVAM Genotoxicity and Carcinogenicity Database of Ames Positive Chemicals This list of 726 chemicals derives from the EURL ECVAM database of curated in vitro and in vivo genotoxicity and carcinogenicity data for Ames positive chemicals, that was compiled from a variety of sources: EU and international regulatory agencies, industry and scientific literature databases. The database is intended to aid in the development and evaluation of alternative approaches to animal testing. It has already been used to evaluate the predictivity of the in vitro Ames test for in vivo genotoxicity and carcinogenicity when used alone or in combination with in vitro assays based on mammalian cells, and for a better characterisation of those cases where the Ames test leads to misleading ('false positive') results (Kirkland et al., Mutation Research, Volumes 775.776, Pages 69.80, 2014). 1 2 3 4 (723 chemicals) download  excel file 
CASEINECSChemical NameSMILES
101-90-6 202-987-5Diglycidyl resorcinol ether, technical gradeC(Oc1cccc(OCC2CO2)c1)C3CO3
101222-80-4 U-71,184CC1=CNC2=C1[C@@]13C[C@@H]1CN(C(=O)C1=CC4=C(N1)C=CC(NC(=O)C1=CC5=C(N1)C=CC=C5)=C4)C3=CC2=O
10318-26-0 DibromodulcitolC(C(C(C(C(CBr)O)O)O)O)Br
106-93-4 203-444-51,2-DibromoethaneBrCCBr
107-06-2 203-458-11,2-DichloroethaneClCCCl
110-57-6 203-779-7trans-1,4-Dichlorobutene-2C\C(=C(\C)/Cl)\Cl
119-90-4 204-355-43,3'-DimethoxybenzidineCOc1cc(ccc1N)c2ccc(N)c(OC)c2
119-93-7 204-358-03,3'-Dimethylbenzidine (free base)Cc1cc(ccc1N)c2ccc(N)c(C)c2
120-83-2 204-429-62,4-DichlorophenolOc1ccc(Cl)cc1Cl
123219-86-3 U-73,975Cc1cnc2c1[C@]38C[C@@H]8CN(\C3=C\C2=O)C(=O)c4cc5cc(ccc5n4)NC(=O)c7coc6ccccc67
126-72-7 204-799-9Tris(2,3-dibromopropyl)phosphateBrCC(Br)COP(=O)(OCC(Br)CBr)OCC(Br)CBr
128714-76-1 3,6-Dinitrobenzopyrene[O-][N+](=O)c2c5c4c(c1ccccc12)ccc3ccc([N+]([O-])=O)c(c34)cc5
1314-84-7 215-244-5Zinc phosphide (Zinctox)P12[Zn]P([Zn]1)[Zn]2
133-07-3 205-088-6N-(Trichloromethylthio)phthalimide [AKA FOLPET]ClC(Cl)(Cl)SN1C(=O)c2ccccc2C1=O
137-17-7 205-282-02,4,5-Trimethylaniline (free base)Cc1cc(C)c(N)cc1C
137-30-4 205-288-3Zinc dimethyldithiocarbamate (Ziram)CN(C)C(=S)S[Zn]SC(=S)N(C)C
140-56-7 205-419-44-Dimethylaminobenzenediazosulfonic acid sodium salt (AKA fenaminosulf)S(\N=N\c1ccc(N(C)C)cc1)(=O)(=O)[O-].[Na+]
1464-53-5 215-979-1DiepoxybutaneC1OC1C2CO2
14816-18-3 238-887-3Valexon / PhoximCCOP(=S)(OCC)O\N=C(/C#N)\c1ccccc1
149330-25-6 604-688-92,6-Dihydroxyethylaminotoluene - COLIPA A138Cc1c(NCCO)cccc1NCCO
15403-45-9 3-3'-DibromomethoxybenzidineO=C(OC)c1cc(ccc1N)c2cc(C(=O)OC)c(N)cc2
15805-73-9 Vinyl carbamateC=COC(=O)N
1582-09-8 216-428-8Trifluralin, technical gradeCCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]
1653-19-6 216-721-02,3-Dichlorobuta-1,3-dieneClC(=C)C(=C)Cl
17309-86-3 5-p-Dimethylaminophenylazoindazolen3cc2cc(/N=N/c1ccc(N(C)C)cc1)ccc2n3
18463-85-9 6-(p-Dimethylaminophenylazo)benzthiazolen2c3ccc(/N=N/c1ccc(N(C)C)cc1)cc3sc2
18463-90-6 5-(p-Dimethylaminophenylazo)benzothiazolen2c3cc(/N=N/c1ccc(N(C)C)cc1)ccc3sc2
21436-96-4 2,4-Xylidine HClCl.Cc1ccc(N)c(C)c1
22089-22-1 244-770-8TrofosfamideClCCN(CCCl)P1(=O)OCCCN1CCCl
2439-35-2 219-460-02-(Dimethylamino)ethyl acrylateCN(C)CCOC(=O)C=C
2451-62-9 219-514-31,3,5-tris(oxyranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trioneO=C1N(CC2CO2)C(=O)N(CC3CO3)C(=O)N1CC4CO4
2524-03-0 219-754-9O,O-Dimethyl phosphorochloridothioateCOP(=S)(Cl)OC
26049-69-4 2-(2,2-Dimethylhydrazino)-4-(5-nitro-2-furyl)thiazoleCN(C)NC1=NC(=CS1)C2=CC=C(O2)[N+](=O)[O-]
2735-04-8 220-355-72,4-Dimethoxyaniline (free base)Nc1ccc(cc1OC)OC
29539-03-5 Dihydroxyindoline HBr COLIPA A147Br.Oc1cc2CCNc2cc1O
306-37-6 206-183-51,2-Dimethylhydrazine 2HClN(NC)C.Cl.Cl
3083-23-6 221-384-83,3,3-Trichloropropylene oxideClC(Cl)(Cl)C1CO1
32362-68-8 6,11-Dimethylbenzo(b)naphthol(2,3-d)thiophenes2c1ccccc1c3c2c(c4c(c3C)cccc4)C
33389-33-2 1,2-Dihydro-2-(5-nitro-2-thienyl)quinazolin-4(3H)-oneC1=CC=C2C(=C1)C(=O)NC(N2)C3=CC=C(S3)[N+](=O)[O-]
34237-98-4 3-3'-DibromobenzidineBrc2cc(c1ccc(N)c(Br)c1)ccc2N
4097-22-7 223-853-22',3'-DideoxyadenosineNc1ncnc2c1ncn2[C@H]3CC[C@@H](CO)O3
4164-28-7 DimethylnitramineCN(C)[N+](=O)[O-]
42011-48-3 2,2,2-Trifluoro-N-[4-(5-nitro-2-furyl)-2-thiazolyl acetamideC1=C(OC(=C1)[N+](=O)[O-])C2=CSC(=N2)NC(=O)C(F)(F)F
42397-64-8 1,6-DinitropyreneC1=CC2=C(C=CC3=C2C4=C1C=CC(=C4C=C3)[N+](=O)[O-])[N+](=O)[O-]
448-97-5 3-3'-DifluorobenzidineFc2cc(c1ccc(N)c(F)c1)ccc2N
482-89-3 207-586-92-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,2 dihydro-3H-indol-3-oneO=C1C(=C2Nc3ccccc3C2=O)Nc4ccccc14
484-23-1 207-605-0DihydralazineNNc1nnc(NN)c2ccccc12
488-41-5 207-676-8DibromomannitolO[C@H](CBr)[C@@H](O)[C@H](O)[C@H](O)CBr
50355-74-3 1-(2,4,6-Trichlorophenyl)-3,3-dimethyltriazeneClc1cc(Cl)cc(Cl)c1/N=N/N(C)C
51-18-3 200-083-5TriethylenemelamineC1CN1c1nc(nc(n1)N1CC1)N1CC1
51-79-6 200-123-1UrethaneCCOC(=O)N
512-56-1 208-144-8TrimethylphosphateCOP(=O)(OC)OC
513-37-1 208-158-4Dimethylvinyl chlorideCC(=CCl)C
51786-53-9 2,5-Xylidine HClCl.Nc1cc(ccc1C)C
52-68-6 200-149-3TrichlorfonCOP(=O)(OC)C(O)C(Cl)(Cl)Cl
533-73-3 208-575-11,2,4-Trihydroxybenzene - COLIPA A33Oc1ccc(O)c(O)c1
542-75-6 208-826-51,3-Dichloropropene (AKA Telone II)ClCC=CCl
55-63-0 200-240-8Trinitroglycerin[O-][N+](=O)OCC(CO[N+](=O)[O-])O[N+](=O)[O-]
551-92-8 209-001-21,2-Dimethyl-5-nitroimidazoleCc1ncc([N+](=O)[O-])n1C
55738-54-0 "trans-2-[(Dimethylamino)methylimino]-5 [2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazole"[O-][N+](=O)c1oc(cc1)\C=C\c2nnc(/N=C/N(C)C)o2
56654-52-5 1,3-Dibutyl-1-nitrosoureaO=C(N(N=O)CCCC)NCCCC
57-14-7 200-316-01,1-DimethylhydrazineCN(C)N
57-97-6 200-359-57,12-Dimethylbenz[a]anthraceneCc1c2ccccc2c(C)c3c1ccc4ccccc34
593-60-2 209-800-6Vinyl bromideBrC=C
60-11-7 200-455-7N,N-Dimethyl-4-aminoazobenzeneCN(C)c1ccc(cc1)N=Nc2ccccc2
60-51-5 200-480-3Dimethoate [AKA phosphorodithioic acid,o,o-dimethyl ester,S-ester with 2-mercapto-N-methylacetamide]CNC(=O)CSP(=S)(OC)OC
607-59-0 4-Dimethylaminoazobenzeneazo-1-naphthaleneN(=N/c2c1ccccc1ccc2)\c3ccc(N(C)C)cc3
609-20-1 210-184-62,6-Dichloro-p-phenylenediamineNc1cc(Cl)c(N)c(Cl)c1
611-06-3 210-248-32,4-Dichloro-1-nitrobenezene[O-][N+](=O)c1ccc(Cl)cc1Cl
613-65-0 4-Dimethylaminoazobenzeneazo-2-naphthaleneN(=N/c2cc1ccccc1cc2)\c3ccc(N(C)C)cc3
62-73-7 200-547-7DichlorvosCOP(=O)(OC)OC=C(Cl)Cl
6271-79-0 228-457-33,3'-DinitrobenzidineNc1ccc(cc1[N+](=O)[O-])c2ccc(N)c(c2)[N+](=O)[O-]
64-67-5 200-589-6Diethyl sulfateCCOS(=O)(=O)OCC
66-75-1 200-631-3Uracil mustardClCCN(CCCl)C1=CNC(=O)NC1=O
683-18-1 211-670-0Dibuthyltin dichlorideCCCC[Sn](Cl)(Cl)CCCC
71-55-6 200-756-31,1,1-TrichloroethaneCC(Cl)(Cl)Cl
7481-89-2 2',3'-Dideoxycytidinec1cn(c(=O)nc1N)[C@H]2CC[C@H](O2)CO
75-01-4 200-831-0Vinyl chloride / ChloroethyleneClC=C
75-09-2 200-838-9DichloromethaneClCCl
75-25-2 200-854-6Tribromomethane (bromoform)BrC(Br)Br
75-35-4 200-864-0Vinylidene chloride / 1,1-DichloroetheneClC(=C)Cl
760-23-6 212-079-03,4-Dichloro-1-buteneClCC(Cl)C=C
77-78-1 201-058-1DimethylsulfateCOS(=O)(=O)OC
78-87-5 201-152-21,2-DichloropropaneCC(Cl)CCl
79-43-6 201-207-0Dichloroacetic acidOC(=O)C(Cl)Cl
79-44-7 201-208-6Dimethylcarbamoyl chlorideCN(C)C(=O)Cl
82617-23-0 Vinyl carbamate epoxideO=C(N)O[C@@H]1OC1
828-00-2 212-579-9Dimethoxane, commercial grade [AKA acetic acid ester with 2,6-dimethyl-m-dioxan-4-ol]CC1CC(OC(=O)C)OC(C)O1
838-95-9 4-DimethylaminostilbeneCN(C)C1=CC=C(C=C1)/C=C/C2=CC=CC=C2
868-85-9 212-783-8Dimethyl hydrogen phosphiteCOP(=O)OC
87-62-7 201-758-72,6-XylidineCc1cccc(C)c1N
88-05-1 201-794-32,4,6-TrimethylanilineCc1cc(C)c(N)c(C)c1
88193-04-8 5,9-Dimethyldibenzo[c,g]carbazolec5c4c(cc3c(c2c1ccccc1c(cc2n3)C)c4ccc5)C
89-61-2 201-923-31,4-Dichloro-2-nitrobenzene[O-][N+](=O)c1cc(Cl)ccc1Cl
91-93-0 3,3'-Dimethoxybenzidine-4,4'-diisocyanteCOc1cc(ccc1N=C=O)c2ccc(c(c2)OC)N=C=O
91-94-1 202-109-03,3'-DichlorobenzidineNc1ccc(cc1Cl)-c2ccc(N)c(Cl)c2
96-12-8 202-479-31,2-Dibromo-3-chloropropaneClCC(Br)CBr
96-13-9 202-480-92,3-Dibromo-1-propanolOCC(Br)CBr
96-18-4 202-486-11,2,3-TrichloropropaneClCC(Cl)CCl
96-23-1 202-491-91,3-Dichloro-2-propanolOC(CCl)CCl
99-54-7 202-764-21,2-Dichloro-4-nitrobenzene[O-][N+](=O)c1ccc(Cl)c(Cl)c1
Records:101:201 Next Back