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DNT list: A database of developmental neurotoxicants Chemicals on this list were derived from published reports or regulatory data from humans, non-human primates, or laboratory mammals. Findings were deemed to be suggestive of adverse neurological outcomes following developmental exposure. To be included on the list there must be positive results from more than one laboratory (Mundy et al., 2009). 1 (71 chemicals) download DNT list excel file 
CASEINECSJRC CODEChemical NameSMILES
112-36-7203-963-7-Diethylene glycol diethyl ether CCOCCOCCOCC
118-74-1204-273-9JRC-000062Hexachlorobenzene Clc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl
1461-22-9215-958-7-Tributyltin chloride CCCC[Sn](Cl)(CCCC)CCCC
22839-47-0245-261-3-AspartameCOC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H](N)CC(O)=O
51-79-6200-123-1JRC-000863Urethane CCOC(=O)N
52-68-6200-149-3JRC-000860Trichlorfon COP(=O)(OC)C(O)C(Cl)(Cl)Cl
52645-53-1258-067-9JRC-000288PermethrinCC1(C)C(C=C(Cl)Cl)C1C(=O)OCC1=CC(OC2=CC=CC=C2)=CC=C1
56-53-1200-278-5JRC-000191DiethylstilbestrolCC\C(=C(\CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
57-22-7200-318-1-VincristineCC[C@]1(O)C[C@H]2C[N@@](C1)CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C=O)[C@@H]7[C@]68CC[N@]9CC=C[C@@](CC)([C@@H]89)[C@@H](OC(C)=O)[C@]7(O)C(=O)OC
71-43-2200-753-7JRC-000046Benzene c1ccccc1
10049-04-4233-162-8JRC-001015Chlorine dioxide [O]Cl=O |^1:0|
127-07-1204-821-7JRC-000701Hydroxyurea NC(=O)NO
17804-35-2241-775-7-Benomyl CCCCNC(=O)N1C(NC(=O)OC)=NC2=C1C=CC=C2
298-46-4206-062-7JRC-000006CarbamazepineNC(=O)N1c2ccccc2C=Cc2ccccc12 |c:11|
300-62-9206-096-2JRC-001019Amphetamine, d-CC(N)CC1=CC=CC=C1
477-30-5207-514-6-Colcemid CN[C@H]1CCC2=CC(OC)=C(OC)C(OC)=C2C2=CC=C(OC)C(=O)C=C12
5224-23-7--Triethyllead CC[Pb](CC)CC |^1:2|
58-89-9200-401-2JRC-000069Lindane Cl[C@@H]1[C@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H](Cl)[C@H]1Cl
62229-50-9263-468-7-Epidermal Growth Factor N([C@H](C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCNC(=N)N)CC(C)C)CCC(=O)O)Cc1c[nH]c2c1cccc2)Cc1c[nH]c2c1cccc2)CCCNC(=N)N)CC(C)C)CC(=O)O)CCCNC(=N)N)[C@@H](O)C)CCC(=O)N)CS)CCCNC(=N)N)CC(=O)O)CO)Cc1ccc(cc1)O)[C@@H](C)CC)[C@@H](C)C)CS)CC(=O)N)CS)[C@@H](O)C)Cc1ccc(cc1)O)CO)CC(=O)O)CC(C)C)CO)CCC(=O)O)[C@@H](C)CC)Cc1[nH]cnc1)CCSC)CS)[C@@H](C)C)CC(=O)N)CC(C)C)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](NC(=O)CNC(=O)[C@H]1N(C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CC(=O)N)CO)Cc2ccc(cc2)O)CCC1)CS)CO)CO)Cc1ccc(cc1)O)CC(=O)O)Cc1ccc(cc1)O)CS
67-56-1200-659-6JRC-000019MethanolOC
7429-90-5231-072-3-Aluminum [AlH3]
76-44-8200-962-3-Heptachlor ClC1C=CC2C1C3(Cl)C(Cl)=C(Cl)C2(Cl)C3(Cl)Cl
108-88-3203-625-9-Toluene Cc1ccccc1
13494-80-9236-813-4-Tellurium [Te]
333-41-5206-373-8JRC-000354DiazinonCCO[P](=S)(OCC)OC1=NC(=NC(C)=C1)C(C)C
439-14-5207-122-5JRC-000009DiazepamC=1(c2c(N(C)C(CN1)=O)ccc(c2)Cl)c1ccccc1
465-65-6207-365-7-Naloxone [H][C@@]12OC3=C4C(C[C@@]5([H])N(CC=C)CC[C@@]14[C@@]5(O)CCC2=O)=CC=C3O
58-25-3200-371-0JRC-000996ChlordiazepoxideCNC1=Nc2ccc(Cl)cc2C(c3ccccc3)=[N+]([O-])C1
64-86-8200-598-5JRC-000007ColchicineCOC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
147-94-4205-705-9JRC-000699Cytosine arabinosideNC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
25013-16-5246-563-8-Butylated hydroxyanisol C(C)(*)(C)C.c1(ccc(O)cc1)OC
60-57-1200-484-5-Dieldrin[H][C@]12C[C@]([H])([C@@H]3O[C@H]13)[C@]1([H])[C@@]2([H])[C@]2(Cl)C(Cl)=C(Cl)[C@@]1(Cl)C2(Cl)Cl
143-50-0205-601-3JRC-000180Chlordecone ClC12C(=O)C3(Cl)C4(Cl)C1(Cl)C1(Cl)C2(Cl)C3(Cl)C4(Cl)C1(Cl)Cl
150-30-1205-756-7-PhenylalanineNC(Cc1ccccc1)C(=O)O
151-67-7205-796-5-HalothaneFC(F)(F)C(Cl)Br
16590-41-3240-649-9-Naltrexone [H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(CC3CC3)[C@]([H])(C4)[C@]1(O)CCC2=O
28434-00-6249-013-5JRC-000295Bioallethrin CC(C)=C[C@@H]1[C@@H](C(=O)O[C@H]2CC(=O)C(CC=C)=C2C)C1(C)C
52-86-8200-155-6JRC-000084Haloperiodol OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
79-06-1201-173-7JRC-000040AcrylamideNC(=O)C=C
124-94-7204-718-7-Triamcinolone [H][C@@]12C[C@@H](O)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
128-37-0204-881-4-Butylated hydroxytoluene Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
134-62-3205-149-7JRC-000353DEET CCN(CC)C(=O)c1cccc(C)c1
329-89-5206-349-7-6-AminonicotinamideNC(=O)c1ccc(N)nc1
36311-69-0--Bis(tri-n-butyltin)oxide -
36643-27-3--Triethyltin CC[Sn+](CC)CC
50-37-3200-033-2-LSD[H][C@@]12CC3=CNC4=CC=CC(=C34)C1=C[C@H](CN2C)C(=O)N(CC)CC
51-52-5200-103-2JRC-000168Propylthiouracil CCCc1cc(=O)[nH]c(=S)[nH]1
56-38-2200-271-7JRC-000071Parathion CCO[P](=S)(OCC)OC1=CC=C(C=C1)[N](=O)=O
584-79-2209-542-4-Allethrin CC(C)=CC1C(C(=O)OC2CC(=O)C(CC=C)=C2C)C1(C)C
63-36-5--Salicylate OC(=O)c1ccccc1O
7631-42-7--Phenylacetate [O-]C(=O)CC1=CC=CC=C1
96-45-7202-506-9JRC-001029Ethylenethiourea S=C1NCCN1
---Methylazoxymethanol Monosodium glutamate -
---Phthalates-
109-86-4203-713-7-Methoxyethanol, 2-COCCO
111-94-4203-922-3-IminodiproprionitrileN#CCCNCCC#N
116-06-3204-123-2-Aldicarb CNC(=O)O\N=C\C(C)(C)SC
1502-95-0216-124-5-Diamorphine hydrochlorideCl.[H][C@@]12OC3=C(OC(C)=O)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])C=C[C@@H]2OC(C)=O
320-67-2206-280-2JRC-000820AzacytidineNC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
5089-96-3--Trimethyltin C[Sn+](C)C
54-11-5200-193-3JRC-000068NicotineCN1CCC[C@H]1C1=CN=CC=C1
60-56-0200-482-4JRC-000502Methimazole [H][C@]12C[C@]([H])([C@@H]3O[C@H]13)[C@]1([H])[C@@]2([H])[C@]2(Cl)C(Cl)=C(Cl)[C@@]1(Cl)C2(Cl)Cl
630-08-0211-128-3-Carbon monoxide [C]#[O] |^1:0|
72-57-1200-786-7JRC-000926Trypan blue Cc1cc(ccc1N=Nc2c(O)c3c(N)cc(cc3cc2S(=O)(=O)O)S(=O)(=O)O)c4ccc(N=Nc5c(O)c6c(N)cc(cc6cc5S(=O)(=O)O)S(=O)(=O)O)c(C)c4
76-99-3200-996-9-Methadone CCC(=O)C(C[C@H](C)N(C)C)(c1ccccc1)c2ccccc2
79-01-6201-167-4-Trichloroethylene Cl\C=C(/Cl)Cl
---PCBs-
12427-38-2235-654-8-Maneb[Mn++].[S-]C(=S)NCCNC([S-])=S
50-35-1200-031-1-Thalidomide O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1
50-53-3200-045-8-ChlorpromazineCN(C)CCCN1C2=CC=CC=C2SC2=C1C=C(Cl)C=C2
51-21-8200-085-6JRC-000064Fluourouracil, 5-FC1=CNC(=O)NC1=O

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